Proximity Effects in Fused Cyclobutanones. Facile Formation of Cage Systems

A. Hassner, Simba Naidorf-Meir, H. E. Gottlieb, I. Goldberg

Research output: Contribution to journalArticlepeer-review

Abstract

Chlorobicyclooctanone 3 on reaction with H2O‒Et3N in acetonitrile at 20 °C produced in high yield four complex dimeric compounds 4‒7. The novel structures produced by C‒C bond formation between tertiary centers were revealed by NMR and X-ray diffraction. Pathways leading from 4 or its diastereomer 14 to cage compounds 5‒7 indicate the importance of proximity effects in these transformations.

Original languageEnglish
Pages (from-to)2442-2445
Number of pages4
JournalJournal of Organic Chemistry
Volume57
Issue number8
DOIs
StatePublished - 1 Apr 1992

Fingerprint

Dive into the research topics of 'Proximity Effects in Fused Cyclobutanones. Facile Formation of Cage Systems'. Together they form a unique fingerprint.

Cite this