TY - JOUR
T1 - Proteins of human follicular fluid
T2 - the blood follicle barrier
AU - Shalgi, R.
AU - Kraicer, P.
AU - Rimon, A.
AU - Pinto, M.
AU - Soferman, N.
PY - 1973
Y1 - 1973
N2 - The composition of the proteins of human follicular fluid and blood plasma was compared. The protein concentration of both was the same. No follicle specific proteins were detected. However, the relative proportions of the proteins were different. Concentrations of albumin, transferrin, IgG, fibrinogen, α2 macroglobulin, IgM, and β1 lipoprotein were studied. Low molecular weight proteins like albumin accumulate in the follicle whereas high molecular weight protein like β1 lipoprotein and IgM are excluded. The blood follicle barrier behaves like a molecular sieve, which allows passage of protein in inverse proportion to molecular weight but, paradoxically, not in inverse proportion to molecular size.
AB - The composition of the proteins of human follicular fluid and blood plasma was compared. The protein concentration of both was the same. No follicle specific proteins were detected. However, the relative proportions of the proteins were different. Concentrations of albumin, transferrin, IgG, fibrinogen, α2 macroglobulin, IgM, and β1 lipoprotein were studied. Low molecular weight proteins like albumin accumulate in the follicle whereas high molecular weight protein like β1 lipoprotein and IgM are excluded. The blood follicle barrier behaves like a molecular sieve, which allows passage of protein in inverse proportion to molecular weight but, paradoxically, not in inverse proportion to molecular size.
UR - http://www.scopus.com/inward/record.url?scp=0015846520&partnerID=8YFLogxK
U2 - 10.1016/s0015-0282(16)39730-8
DO - 10.1016/s0015-0282(16)39730-8
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AN - SCOPUS:0015846520
VL - 24
SP - 429
EP - 434
JO - Unknown Journal
JF - Unknown Journal
IS - 6
ER -