Protein multifunctionality: Principles and mechanisms

Joseph Z. Zaretsky*, Daniel H. Wreschner

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

18 Scopus citations

Abstract

In the review, the nature of protein multifunctionality is analyzed. In the first part of the review the principles of structural/functional organization of protein are discussed. In the second part, the main mechanisms involved in development of multiple functions on a single gene product(s) are analyzed. The last part represents a number of examples showing that multifunctionality is a basic feature of biologically active proteins.

Original languageEnglish
Pages (from-to)99-136
Number of pages38
JournalTranslational Oncogenomics
Volume2008
Issue number3
StatePublished - 2008

Keywords

  • Function
  • Multifunctionality
  • Protein
  • Structure

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