Prostaglandins—a role in Adhesion Formation an Experimental Study

A. Golan*, O. Stolik, S. Wexler, R. Langer, A. Ber, M. P. David

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The effect of intraperitoneal application of prostaglandins F2Alpha and E2 on adhesion formation was studied in the rat after traumatizing to the uterine serosa. Prostaglandins applied locally were found to increase intraperitoneal adhesion formation at the injury site, in comparison with controls. the effect of intraperitoneal application of prostaglandins F2Alpha and E2 on fibroblastic proliferation was examined in vitro, by fibroblastic cell culture of rat kidney, human kidney and human prepuce. No direct effect of prostaglandins on fibroblast proliferation could be demonstated. It is concluded that prostaglandins play an important role in the process of adhesion formation. This effect in not related to fibrobalast proliferation. 1990 Acta Obstet Gynecol Scand

Original languageEnglish
Pages (from-to)339-341
Number of pages3
JournalActa Obstetricia et Gynecologica Scandinavica
Volume69
Issue number4
DOIs
StatePublished - Jan 1990
Externally publishedYes

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