Prostaglandin production by the oocyte cumulus complex around the time of fertilization and the effect of prostaglandin e on the development of the early bovine embryo

M. Gurevich, E. Harel-Markowitz, S. Marcus, L. S. Shore, M. Shemesh

Research output: Contribution to journalArticlepeer-review

Abstract

The oocyte-cumulus complex (25 oocytes per 250 /tL medium) produced prostaglandin-F2a (PGF2a) and PGE2 during maturation, immediately following fertilization and for at least 48 h after fertilization. The data suggest that PG production is important in the development of the oocyte; addition of PGE2 (5 ng mL-1) to the fertilization medium increased the rate of cleavage and groups of oocytes with low cleavage rates produced far less PG than groups with high cleavage rates. Measurement of PG in the maturation medium could therefore be a means of assessing the suitability of oocytes for fertilization.

Original languageEnglish
Pages (from-to)281-283
Number of pages3
JournalReproduction, Fertility and Development
Volume5
Issue number3
DOIs
StatePublished - 1993
Externally publishedYes

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