Prolonged fever as a presenting symptom in adrenal tumors

J. M. Klausner, R. Nakash, M. Inbar, M. Gutman, S. Lelcuk, R. R. Rozin

Research output: Contribution to journalArticlepeer-review


Four patients with adrenal tumors in whom prolonged fever was the foremost symptom are presented. Two of the patients had nonfunctional adrenocortical carcinoma, one had a pheochromocytoma without adrenergic hyperactivity, and in the fourth, an aldosteronoma was found. Only in 1 case was the tumor (pheochromocytoma) resectable and this patient before afebrile post surgery. A review of the literature revealed that fever is encountered in 6-10% of cases with adrenal tumors, sometimes as the first manifestation of disease. However, a survey of the large series of fever of unknown origin revealed no mention of adrenal tumors in that group of solid tumors which many cause prolonged fever.

Original languageEnglish
Pages (from-to)15-17
Number of pages3
Issue number1
StatePublished - 1988
Externally publishedYes


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