Programmed dynamic topologies in DNA catenanes

Johann Elbaz, Zhen Gang Wang, Fuan Wang, Itamar Willner

Research output: Contribution to journalArticlepeer-review

Abstract

Linking in: Two-ring and three-ring catenane nanostructures that are made from sequences of DNA have been shown to undergo programmed and reversible reconfiguration across defined topologies by using strand displacement. The switchable nature of the configurations may enable a more flexible approach to the transport and delivery of molecular cargoes, or for the use of such structures as labels in an intracellular environment.

Original languageEnglish
Pages (from-to)2349-2353
Number of pages5
JournalAngewandte Chemie - International Edition
Volume51
Issue number10
DOIs
StatePublished - 5 Mar 2012
Externally publishedYes

Keywords

  • DNA structures
  • catenanes
  • molecular devices
  • nanostructures
  • strand displacement

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