Programmable comprehensive controller for multi-color 3D confocal spinning-disk image scanning microscope

Eli Flaxer*, Lanna Bram, Alona Flaxer, Yael Roichman, Yuval Ebenstein

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

This paper introduces a compact, portable, and highly accurate triggering control system for a 3D confocal spinning-disk image scanning microscope (CSD-ISM). Building upon on our previously published research, we expanded the hardware of the controller and synchronized it with a sub-micron translator which scans the object in the z-direction. As well as expanding the hardware, the software also was extended from previously published work similarly as it is stated for hardware while allowing full control over the 3D movement. We showed a clear and smooth 3D image made up of a collection of 2D images at different heights.

Original languageEnglish
Article number113888
JournalUltramicroscopy
Volume257
DOIs
StatePublished - Mar 2024

Keywords

  • Fluorescence microscopy
  • Image scanning microscope
  • Spinning-disk microscope

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