Prognosis of stress-only SPECT myocardial perfusion imaging with prone imaging

Ariel Gutstein*, Tamir Bental, Ajejandro Solodky, Israel Mats, Nili Zafrir

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Background: Stress-only single-photon emission computed tomography myocardial perfusion imaging (SO SPECT MPI) is associated with similarly benign prognosis as stress-rest SPECT MPI. However, previous studies have used attenuation correction rather than prone imaging to increase the rate of SO studies. Objectives: To assess the prognosis of SO SPECT MPI performed with prone imaging. Methods: We performed a retrospective cohort analysis of all patients who underwent a Tc-99m gated SPECT MPI over a 58-month period. Results: Two thousand four hundred and sixty five patients were followed up. Of them, 1114 (45.2%) patients had a SO supine test, 388 (15.7%) underwent a SO supine and prone test, and the remaining 963 (39.1%) patients underwent a full stress-rest SPECT MPI. There was a similar annual mortality rate between the SO supine/prone group (1.3%), the SO supine (1.5%), and the stress-rest (1.5%) group (P = 0.47). Patients in the stress-rest group were significantly more likely to suffer from myocardial infarction (MI) as compared to the other two groups with an annual rate of 0.7% as compared to 0.4% (P = 0.049). Conclusions: Normal supine-prone SO SPECT MPI is associated with a similarly benign prognosis as stress-rest SPECT MPI. The adjunction of prone imaging to the stress supine significantly increases the rate of SO SPECT MPI.

Original languageEnglish
Pages (from-to)809-816
Number of pages8
JournalJournal of Nuclear Cardiology
Issue number3
StatePublished - 1 Jun 2018


  • Myocardial perfusion imaging: SPECT
  • diagnostic and prognostic application
  • dipyridamole
  • infarction
  • myocardial


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