Production of colony-stimulating activity (CSA) by T-chronic lymphocyte leukemia cells

D. Douer, I. Ben-Bassat, N. Shaked, B. Ramot

Research output: Contribution to journalArticlepeer-review


T-lymphocytes are probably involved in regulating myelopoiesis. We show that homogeneous populations of leukemic T-lymphocytes freshly obtained from two patients with T cell chronic lymphocytic leukemia produce colony-stimulating activity. The cells from both patients showed the antigenic and biochemical phenotype of the mature T-lymphocyte of the helper subset. This adds further support to the view that helper T-lymphocytes may regulate hematopoiesis in addition to their role in the immune function.

Original languageEnglish
Pages (from-to)656-661
Number of pages6
JournalIsrael Journal of Medical Sciences
Issue number8
StatePublished - 1985
Externally publishedYes


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