TY - JOUR
T1 - Procedure-to-delivery interval after late amniocentesis and the need for routine antenatal corticosteroids
AU - Leytes, Sophia
AU - Haratz, Karina Krajden
AU - Grin, Leonti
AU - Shwartz, Tomer
AU - Zohav, Efraim
AU - Weisz, Boaz
AU - Lipitz, Shlomo
AU - Maymon, Ron
AU - Bardin, Ron
AU - Gilboa, Yinon
AU - Kleiner, Ilia
AU - Kashanian, Alon
AU - Lev, Dorit
AU - Bar, Jacob
AU - Shalev, Josef
AU - Gindes, Liat
N1 - Publisher Copyright:
© 2020 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2022
Y1 - 2022
N2 - Objectives: The aim of this study is to assess the procedure-to-delivery interval (PDI), the obstetric complications, and the early neonatal outcome in patients that did or did not receive glucocorticosteroids (GCSs) before third-trimester amniocentesis (TTA). Methods: A retrospectively analysis of 445 TTA procedures divided into two groups based on the administration (study group = 220 patients) or not (control group = 225 patients) of GCSs before TTA. The PDI was calculated for all patients. Obstetric and neonatal outcomes were compared between the groups. Results: The rate of procedure-associated complications was similar between the groups. The mean PDI was 47.2 ± 16.8 days. The overall incidence of preterm birth was 11.7%; 9% delivered between 34 and 37 weeks and 2.7% between 28 and 34 weeks. Only nine patients (2%) delivered within seven days following TTA. The incidence of respiratory distress syndrome in the study and control groups was 1.8% and 1.3%, p =.71, respectively. There were no significant differences in other neonatal outcomes in term and preterm deliveries between the study and control groups. Conclusions: In the present study, the administration of glucocorticoids prior to TTA did not reduce the rates of neonatal complications, which was similar in both groups and not higher than the general population.
AB - Objectives: The aim of this study is to assess the procedure-to-delivery interval (PDI), the obstetric complications, and the early neonatal outcome in patients that did or did not receive glucocorticosteroids (GCSs) before third-trimester amniocentesis (TTA). Methods: A retrospectively analysis of 445 TTA procedures divided into two groups based on the administration (study group = 220 patients) or not (control group = 225 patients) of GCSs before TTA. The PDI was calculated for all patients. Obstetric and neonatal outcomes were compared between the groups. Results: The rate of procedure-associated complications was similar between the groups. The mean PDI was 47.2 ± 16.8 days. The overall incidence of preterm birth was 11.7%; 9% delivered between 34 and 37 weeks and 2.7% between 28 and 34 weeks. Only nine patients (2%) delivered within seven days following TTA. The incidence of respiratory distress syndrome in the study and control groups was 1.8% and 1.3%, p =.71, respectively. There were no significant differences in other neonatal outcomes in term and preterm deliveries between the study and control groups. Conclusions: In the present study, the administration of glucocorticoids prior to TTA did not reduce the rates of neonatal complications, which was similar in both groups and not higher than the general population.
KW - Late amniocentesis
KW - antenatal corticosteroids
KW - neonatal complications
KW - preterm delivery
KW - respiratory distress syndrome
KW - third trimester amniocentesis
UR - http://www.scopus.com/inward/record.url?scp=85096536466&partnerID=8YFLogxK
U2 - 10.1080/14767058.2020.1849115
DO - 10.1080/14767058.2020.1849115
M3 - מאמר
C2 - 33225769
AN - SCOPUS:85096536466
VL - 35
SP - 4338
EP - 4345
JO - Journal of Maternal-Fetal and Neonatal Medicine
JF - Journal of Maternal-Fetal and Neonatal Medicine
SN - 1476-7058
IS - 22
ER -