Probiotics for the prevention of nosocomial diarrhea in children

Iva Hojsak, Hania Szajewska*, Roberto B. Canani, Alfredo Guarino, Flavia Indrio, Sanja Kolacek, Rok Orel, Raanan Shamir, Yvan Vandenplas, Johannes B. Van Goudoever, Zvi Weizman

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

44 Scopus citations


This document provides recommendations developed by the ESPGHAN Working Group on Probiotics and Prebiotics on the role of probiotics in the prevention of nosocomial diarrhea in children based on a systematic review of previously completed systematic reviews and of subsequently published randomized controlled trials. The quality of evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation guidelines. Recommendations were given only if at least 2 randomized controlled trials examined the same probiotic strain. Based on currently available evidence the Working Group recommends using Lactobacillus rhamnosus GG if the use of probiotics for preventing nosocomial diarrhea in children is considered.

Original languageEnglish
Pages (from-to)3-9
Number of pages7
JournalJournal of Pediatric Gastroenterology and Nutrition
Issue number1
StatePublished - 1 Jan 2018


  • Guideline
  • Healthcare-associated
  • Hospital-acquired
  • Microbiota
  • Randomized controlled trial
  • Systematic review


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