Principle: A tool for associating genes with diseases via network propagation

Assaf Gottlieb, Oded Magger, Igor Berman, Eytan Ruppin, Roded Sharan

Research output: Contribution to journalArticlepeer-review

Abstract

PRINCIPLE is a Java application implemented as a Cytoscape plug-in, based on a previously published algorithm, PRINCE. Given a query disease, it prioritizes disease-related genes based on their closeness in a protein-protein interaction network to genes causing phenotypically similar disorders to the query disease.

Original languageEnglish
Article numberbtr584
Pages (from-to)3325-3326
Number of pages2
JournalBioinformatics
Volume27
Issue number23
DOIs
StatePublished - Dec 2011

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