Primary subacute osteomyelitis of the axial and appendicular skeleton

E. Ezra, O. Khermosh, A. Assia, Z. Spirer, S. Wientroub*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Subacute osteomyelitis is not uncommon. Owing to its insidious onset, mild symptoms, and inconsistent supportive laboratory data, diagnosis and treatment are usually delayed. We report a retrospective review of 28 consecutive patients with subacute hematogenous osteomyelitis. Based on a review of the literature and our experience, we reached the following conclusions: Recognition of the subacute form of osteomyelitis as a separate clinical condition distinct from the acute form will lead to early institution of an aggressive, conservative treatment protocol. We adopted Robert’s modification of Gledhill’s classification, but believed that one type of radiologic presentation was missing and should be added as type VII–that is, sclerosis of flat bones with neither erosive nor destructive processes. This disease responds very favorably to appropriate antibiotic therapy. Surgery should be reserved for persistent infection symptoms despite appropriate therapy or performed when lesions are indistinguishable from bone tumors by use of all available imaging modalities.

Original languageEnglish
Pages (from-to)148-152
Number of pages5
JournalJournal of Pediatric Orthopaedics Part B
Issue number2
StatePublished - 1992


  • Bone infection
  • Brodie’s abscess
  • Diaphyseal osteomyelitis
  • Epiphyseal osteomyelitis
  • Subacute hematogenous osteomyelitis


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