Primary hyperparathyroidism, psychiatric manifestations, diagnosis and management

Baruch Spivak*, Marguerite Radvan, Richard Ohring, Abraham Weizman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Mental manifestations of primary hyperparathyroidism simulate a wide spectrum of psychiatric disorders. Definitive surgical treatment results in long-lasting full recovery. The 2 cases presented demonstrate this. The clinical diagnostic and therapeutic aspects of primary hyperparathyroidism, with an emphasis on neuropsychiatric manifestations, are discussed. Early diagnosis of hypercalcemia can prevent unnecessary and potentially harmful treatment with antidepressive, anxiolytic or antipsychotic drugs, which can further depress the cognitive state of the patients, and can aggravate the mental symptoms.

Original languageEnglish
Pages (from-to)38-44
Number of pages7
JournalPsychotherapy and Psychosomatics
Issue number1
StatePublished - 1989


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