Prevention of tumor spread by matrix metalloproteinase-9 inhibition: Old drugs, new concept

Shaul Lev; Boris Gilburd; Niza Lahat; Yehuda Shoenfeld

doi:10.1016/S0953-6205(02)00011-0

Prevention of tumor spread by matrix metalloproteinase-9 inhibition: Old drugs, new concept

Shaul Lev, Boris Gilburd, Niza Lahat, Yehuda Shoenfeld^*

^*Corresponding author for this work

Clinical Departments

Tel Aviv University

Research output: Contribution to journal › Review article › peer-review

15 Scopus citations

Abstract

In the following review we will discuss some familiar drugs with potential use as adjuvant anti-neoplastic agents. We will highlight their unfamiliar property of being able to inhibit matrix metalloproteinase-9 activity, which has recently been proven to play a key role in cancer spread. These drugs' high-safety profile may allow clinicians to construct new anti-cancer protocols that may prove to be less toxic alternatives to those commonly used.

Original language	English
Pages (from-to)	101-103
Number of pages	3
Journal	European Journal of Internal Medicine
Volume	13
Issue number	2
DOIs	https://doi.org/10.1016/S0953-6205(02)00011-0
State	Published - 2002

Keywords

Aspirin
HMG-CoA reductase inhibitors
IVIG
Intravenous gammaglobulins
Metalloproteinases
Metastasis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0953-6205(02)00011-0

Cite this

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abstract = "In the following review we will discuss some familiar drugs with potential use as adjuvant anti-neoplastic agents. We will highlight their unfamiliar property of being able to inhibit matrix metalloproteinase-9 activity, which has recently been proven to play a key role in cancer spread. These drugs' high-safety profile may allow clinicians to construct new anti-cancer protocols that may prove to be less toxic alternatives to those commonly used.",

keywords = "Aspirin, HMG-CoA reductase inhibitors, IVIG, Intravenous gammaglobulins, Metalloproteinases, Metastasis",

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AU - Gilburd, Boris

AU - Lahat, Niza

AU - Shoenfeld, Yehuda

PY - 2002

Y1 - 2002

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KW - HMG-CoA reductase inhibitors

KW - IVIG

KW - Intravenous gammaglobulins

KW - Metalloproteinases

KW - Metastasis

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Prevention of tumor spread by matrix metalloproteinase-9 inhibition: Old drugs, new concept

Abstract

Keywords

UN SDGs

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