Prevalence of congenital anomalies and neonatal complications in the offspring of diabetic mothers in Israel

M. Hod, P. Merlob, S. Friedman, Y. Rusecki, A. Schoenfeld, J. Ovadia

Research output: Contribution to journalArticlepeer-review

Abstract

The prevalence of diabetes in pregnancy and its fetal and perinatal consequences in a large population of Israeli pregnant women during the last decade are presented. The study population consisted of 878 gestational diabetic women, 132 pre-gestational diabetic women, and 380 healthy pregnant women who served as controls. Minor congenital anomalies ranging between 19.4 and 20.5%, major congenital anomalies between 1.80 and 6.82%, and neonatal complications, such as macrosomia (5.6-25.0%), hypoglycemia (0.9-7.8%), hyperbilirubinemia (8.2-16.7%), hypocalcemia (2.7-5.5%) and polycythemia (3.8-13.3%), were observed in the study population. Despite meticulous maternal glucose control, we could not entirely eliminate fetal and neonatal complications. The definition of the normal and abnormal fetal intrauterine metabolic environment remains to be elucidated.

Original languageEnglish
Pages (from-to)498-502
Number of pages5
JournalIsrael Journal of Medical Sciences
Volume27
Issue number8-9
StatePublished - 1991
Externally publishedYes

Keywords

  • Minor and major congenital anomalies
  • Offspring of diabetic mothers
  • Perinatal complications
  • Pregnancy diabetes

Fingerprint

Dive into the research topics of 'Prevalence of congenital anomalies and neonatal complications in the offspring of diabetic mothers in Israel'. Together they form a unique fingerprint.

Cite this