Prevalence and correlates of diphtheria toxin antibodies among young adults in Israel

Dani Cohen, Eli Katzenelson, Manfred Green, Raphael Slepon, Hillel Bercovier, Yehuda Danon

Research output: Contribution to journalArticlepeer-review

Abstract

The paucity of information about immunity against diphtheria of young adults in Israel prompted us to analyse sera from a random sample of 480 recruits (263 males and 217 females) aged 18-19 years. Antitoxin antibody levels were determined by means of ELISA. Of the recruits 58·1 % had antibody values greater than 0·1 IU/ml; 38·5 % had amounts between 0·01 and 0·1 IU/ml, which is considered low when using the ELISA method, and 3·3 % had less than 0·1 IU/ml. The results of this study suggest that a booster dose of antidiphtheria vaccine should be given to adults in Israel in order to ensure adequate antibody levels.

Original languageEnglish
Pages (from-to)117-121
Number of pages5
JournalJournal of Infection
Volume23
Issue number2
DOIs
StatePublished - Sep 1991
Externally publishedYes

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