Prevalence and clinical characteristics of adrenal incidentalomas in potential kidney donors

Alon Grossman*, Ronit Koren, Amit Tirosh, Rachel Michowiz, Zippora Shohat, Ruth Rahamimov, Eytan Mor, Ilan Shimon, Eyal Robenshtok

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

ABSTRACT: Background: The prevalence of adrenal incidentalomas (AIs) in asymptomatic individuals is unknown. This study evaluated the prevalence of AIs in healthy kidney donors in whom pre-operative computed tomography (CT) is performed routinely. Methods: All potential kidney donors evaluated at the Rabin Medical Center who had routine abdominal CT were identified and their medical records were retrospectively reviewed. Subjects who had normal CT scans were compared with those with a finding of an AI, evaluating demographic (age, body mass index, systolic and diastolic blood pressure) and laboratory variables (glucose, sodium, potassium, calcium, phosphorus, albumin and creatinine). In addition, prevalence of hypertension, rate of donation and surgical mortality were compared between the two groups. Results: CT was performed in 673 potential kidney donors. Of these, 645 had a normal CT and 28 (4.2%) had evidence of an AI. Those with AIs had a similar prevalence of hypertension, kidney donation and surgical mortality as those with a normal CT. Those with AIs were older (50.93 ± 11.1 versus 43.76 ± 11.1 years) but other demographic variables were similar; laboratory variables were also similar except for slightly lower albumin and creatinine in those with AIs. Conclusions: The prevalence of AIs is high even in healthy asymptomatic individuals.

Original languageEnglish
Pages (from-to)98-102
Number of pages5
JournalEndocrine Research
Volume41
Issue number2
DOIs
StatePublished - 2 Apr 2016

Keywords

  • Adrenal
  • incidentaloma
  • kidney donors

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