Preterm Human Milk Macronutrient and Energy Composition: A Systematic Review and Meta-Analysis

Francis B. Mimouni, Ronit Lubetzky, Sivan Yochpaz, Dror Mandel

Research output: Contribution to journalReview articlepeer-review

Abstract

This study is a systematic review of the macronutrient and energy composition of preterm human milk to enable the practicing neonatologist to make informed nutritional decisions in preterm infants. Meta-analyses were conducted in all the studies that reported total energy, true protein, fat, and lactose. Protein content decreased massively (by one-half) and significantly from day 1 to 3 at week 10 to 12. There was a significant linear increase in fat, lactose, and energy content during the same timeframe. Theoretic calculations on energy and macronutrient intake of preterm infants must be made according to a lactation time-specific manner.

Original languageEnglish
Pages (from-to)165-172
Number of pages8
JournalClinics in Perinatology
Volume44
Issue number1
DOIs
StatePublished - 1 Mar 2017

Keywords

  • Breastfeeding
  • Human milk
  • Macronutrients
  • Preterm

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