The effect of saline extract of midgut from Oriental hornet (Vespa orientalis) larvae on spontaneous and evoked release of acetylcholine at the frog sartorius neuromuscular junction was studied. The extract caused a 25-60% increase of the e.p.p. amplitude during the first 10-15 min, followed by a slow decrease, sometimes to below the control level. Neither the amplitude nor the size or shape of the miniature end-plate potentials changed. The changes in e.p.p. quantal content paralleled exactly the changes in the e.p.p. amplitude, which suggests that the activity of the extract is presynaptic.
|Number of pages||4|
|State||Published - 1980|