Preparing for laboratory automation and consolidation—Establishing the validity of pediatric-like low-volume urine samples in boric-acid containing tubes

Or Kriger*, Natasha Belausov, Shiraz Gefen-Halevi, Nadezda Savieva, Sharon Amit

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Microbiological services consolidation has increased the usage of preservative-containing urine tubes, potentially inhibiting pathogens in low-volume pediatric urine samples, yielding false-negative results. Our study demonstrates comparable growth with 1 ml versus the recommended 3 ml urine, following different shipping intervals. We advocate for regulators to consider similar large-scale validations, ensuring results’ consistency.

Original languageEnglish
Article number116121
JournalDiagnostic Microbiology and Infectious Disease
Volume108
Issue number2
DOIs
StatePublished - Feb 2024

Keywords

  • Lab automation
  • Low-volume urine
  • Preservative
  • Urine culture

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