Preparation, characterization and manipulation of conjugates between gold nanoparticles and DNA

Gennady Eidelshtein; Moran Fattal; Gavriel Avishai; Benjamin Kempinski; Clelia Giannini; Alexander Kotlyar

doi:10.3390/nano6090167

Preparation, characterization and manipulation of conjugates between gold nanoparticles and DNA

Gennady Eidelshtein, Moran Fattal, Gavriel Avishai, Benjamin Kempinski, Clelia Giannini, Alexander Kotlyar^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Here we described the preparation and characterization by atomic force microscopy of dumbbell-shaped conjugates between 450 bp double-stranded DNA polymer, poly(dG)-poly(dC), and 5 nm gold nanoparticles (GNPs). We have demonstrated that the size of the nanoparticles in the conjugates can be increased in a controlled fashion. Application of the conjugates for measuring the electrical conductivity of DNA is discussed.

Original language	English
Article number	167
Journal	Nanomaterials
Volume	6
Issue number	9
DOIs	https://doi.org/10.3390/nano6090167
State	Published - 8 Sep 2016

Keywords

Atomic force microscopy
DNA nanotechnology
Gold nanoparticles
Poly(dG)-poly(dC)

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abstract = "Here we described the preparation and characterization by atomic force microscopy of dumbbell-shaped conjugates between 450 bp double-stranded DNA polymer, poly(dG)-poly(dC), and 5 nm gold nanoparticles (GNPs). We have demonstrated that the size of the nanoparticles in the conjugates can be increased in a controlled fashion. Application of the conjugates for measuring the electrical conductivity of DNA is discussed.",

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AU - Fattal, Moran

AU - Avishai, Gavriel

AU - Kempinski, Benjamin

AU - Giannini, Clelia

AU - Kotlyar, Alexander

PY - 2016/9/8

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KW - Atomic force microscopy

KW - DNA nanotechnology

KW - Gold nanoparticles

KW - Poly(dG)-poly(dC)

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Preparation, characterization and manipulation of conjugates between gold nanoparticles and DNA

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Keywords

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