Preparation, characterization and manipulation of conjugates between gold nanoparticles and DNA

Gennady Eidelshtein, Moran Fattal, Gavriel Avishai, Benjamin Kempinski, Clelia Giannini, Alexander Kotlyar*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Here we described the preparation and characterization by atomic force microscopy of dumbbell-shaped conjugates between 450 bp double-stranded DNA polymer, poly(dG)-poly(dC), and 5 nm gold nanoparticles (GNPs). We have demonstrated that the size of the nanoparticles in the conjugates can be increased in a controlled fashion. Application of the conjugates for measuring the electrical conductivity of DNA is discussed.

Original languageEnglish
Article number167
JournalNanomaterials
Volume6
Issue number9
DOIs
StatePublished - 8 Sep 2016

Keywords

  • Atomic force microscopy
  • DNA nanotechnology
  • Gold nanoparticles
  • Poly(dG)-poly(dC)

Fingerprint

Dive into the research topics of 'Preparation, characterization and manipulation of conjugates between gold nanoparticles and DNA'. Together they form a unique fingerprint.

Cite this