Prenatal ultrasonographic diagnosis of persistent hyperplastic primary vitreous

E. Katorza*, M. Rosner, Y. Zalel, Y. Gilboa, R. Achiron

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Persistent hyperplastic primary vitreous (PHPV) is a rare developmental malformation of the eye characterized by the presence of a vascular membrane located behind the lens. We report, for the first time in the literature, the identification on ultrasound examination of bilateral cataract and thickened hyaloid artery-lens junction, leading to a diagnosis of bilateral PHPV, in a fetus at 23 weeks' gestation. Histological examination at postmortem confirmed the prenatal diagnosis of bilateral PHPV and cataract. A thorough ultrasound examination of the fetal eye in cases with cataract is recommended.

Original languageEnglish
Pages (from-to)226-228
Number of pages3
JournalUltrasound in Obstetrics and Gynecology
Issue number2
StatePublished - Aug 2008


  • Fetal cataract
  • PHPV
  • Persistent hyperplastic primary vitreous
  • Ultrasound diagnosis


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