TY - JOUR
T1 - Prenatal stress and risk of spontaneous abortion
AU - Wainstock, Tamar
AU - Lerner-Geva, Liat
AU - Glasser, Saralee
AU - Shoham-Vardi, Ilana
AU - Anteby, Eyal Y.
PY - 2013/4
Y1 - 2013/4
N2 - OBJECTIVE: The aim of this study was to evaluate the association between exposure to life-threatening rocket attacks and spontaneous abortions (SAs). STUDY DESIGN: This is a historical cohort study comparing 1345 pregnancies of female residents of a town exposed to rocket attacks with 2143 pregnancies of female residents of an unexposed town. Demographic and medical data were obtained from hospital records and exposure information from official local databases. Intensity of exposure was calculated for preconception and pregnancy periods. RESULTS: Compared with unexposed group, women in the exposed group had higher rates of SA (6.9% versus 4.7%, adjusted odds ratio = 1.59, 95% confidence interval = 1.17-2.2, p = .003). Intensity of preconception and pregnancy exposure were nonlinearly associated with SA risk; both the highest and the lowest quintiles of exposure were associated with increased risk of SA. CONCLUSIONS: Stress during preconception and pregnancy was associated with increased risk of SA.
AB - OBJECTIVE: The aim of this study was to evaluate the association between exposure to life-threatening rocket attacks and spontaneous abortions (SAs). STUDY DESIGN: This is a historical cohort study comparing 1345 pregnancies of female residents of a town exposed to rocket attacks with 2143 pregnancies of female residents of an unexposed town. Demographic and medical data were obtained from hospital records and exposure information from official local databases. Intensity of exposure was calculated for preconception and pregnancy periods. RESULTS: Compared with unexposed group, women in the exposed group had higher rates of SA (6.9% versus 4.7%, adjusted odds ratio = 1.59, 95% confidence interval = 1.17-2.2, p = .003). Intensity of preconception and pregnancy exposure were nonlinearly associated with SA risk; both the highest and the lowest quintiles of exposure were associated with increased risk of SA. CONCLUSIONS: Stress during preconception and pregnancy was associated with increased risk of SA.
KW - prenatal maternal stress
KW - spontaneous abortion
UR - http://www.scopus.com/inward/record.url?scp=84876287585&partnerID=8YFLogxK
U2 - 10.1097/PSY.0b013e318280f5f3
DO - 10.1097/PSY.0b013e318280f5f3
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C2 - 23362503
AN - SCOPUS:84876287585
SN - 0033-3174
VL - 75
SP - 228
EP - 235
JO - Psychosomatic Medicine
JF - Psychosomatic Medicine
IS - 3
ER -