TY - CHAP
T1 - Preferential efficacy of serotonergic medication in obsessive-compulsive disorder
T2 - From practice to theory
AU - Iancu, Iulian
AU - Dannon, Pinhas N.
AU - Lustig, Michal
AU - Sasson, Yehuda
AU - Zohar, Joseph
N1 - Publisher Copyright:
© 2000 Lawrence Erlbaum Associates, Inc.
PY - 2017/1/1
Y1 - 2017/1/1
N2 - Until the early 1980s, obsessive-compulsive disorder (OCD) was considered a treatment-refractory, chronic condition of psychological origins. Treatment strategies included dynamic psychotherapy, which in general was of little benefit, and a variety of pharmacological treatments that had been tried without much success (Salzman & Thaler, 1981). The observation that clomipramine, a tricyclic antidepressant with a serotonergic profile, is effective in treating symptoms of OCD has resulted in intense interest in the relation between serotonin and this disorder (FemandezCordoba & Lopez-Ibor, 1967; Renynghe de Voxrie, 1968; Yaryura-Tobias, Neziroglu, & Bergman, 1976).
AB - Until the early 1980s, obsessive-compulsive disorder (OCD) was considered a treatment-refractory, chronic condition of psychological origins. Treatment strategies included dynamic psychotherapy, which in general was of little benefit, and a variety of pharmacological treatments that had been tried without much success (Salzman & Thaler, 1981). The observation that clomipramine, a tricyclic antidepressant with a serotonergic profile, is effective in treating symptoms of OCD has resulted in intense interest in the relation between serotonin and this disorder (FemandezCordoba & Lopez-Ibor, 1967; Renynghe de Voxrie, 1968; Yaryura-Tobias, Neziroglu, & Bergman, 1976).
UR - http://www.scopus.com/inward/record.url?scp=85068783033&partnerID=8YFLogxK
U2 - 10.4324/9781315561073-29
DO - 10.4324/9781315561073-29
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AN - SCOPUS:85068783033
SN - 0805828370
SN - 9781138674783
SP - 303
EP - 313
BT - Obsessive-Compulsive Disorder
PB - Taylor and Francis
ER -