Preexisting antibodies to homologous colonization factors and heat-labile toxin in serum, and the risk to develop enterotoxigenic Escherichia coli-associated diarrhea

Joshua Tobias, Kerstin Andersson, Anya Bialik, Dani Cohen

Research output: Contribution to journalArticlepeer-review

Abstract

Preexisting serum immunoglobulin (Ig) A and IgG titers against colonization factors and heat-labile toxin of enterotoxigenic Escherichia coli (ETEC) were examined in young adults who subsequently developed ETEC-associated diarrhea and in healthy matched controls. The data suggest an inverse association between the antibody titers against colonization factors, but not heat-labile toxin, and development of ETEC-associated diarrhea.

Original languageEnglish
Pages (from-to)229-231
Number of pages3
JournalDiagnostic Microbiology and Infectious Disease
Volume60
Issue number2
DOIs
StatePublished - Feb 2008

Keywords

  • Colonization factors
  • Diarrhea
  • ETEC
  • Preexisting antibodies

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