Abstract
Isotype-specific enzyme-linked immunosorbent assays have been developed to assess anti-Ro/SSA and anti-La/SSB IgG subclasses in 31 patients with primary Sjogren's syndrome. The anti-Ro/SSA antibody production was largely restricted IgG1, whilst the anti-La/SSB subclass distribution varied from one patient to another. IgG2 and IgG3 anti-La/SSB were more frequent in those patients with extraglandular complications.
Translated title of the contribution | Predominance of IgG1 subclasse among anti-Ro/SSA and anti-La/SSB antibodies during primary Gougerot-Sjogren syndrome |
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Original language | French |
Pages (from-to) | 446 |
Number of pages | 1 |
Journal | Revue de Medecine Interne |
Volume | 14 |
Issue number | 6 |
State | Published - 1993 |
Externally published | Yes |