PREDOMINANCE DE LA SOUS-CLASSE IGG1 PARMI LES ANTICORPS ANTI-RO/SSA, MAIS PAS PARMI LES ANTICORPS ANTI-LA/SSB, AU COURS DE SYNDROME DE GOUGEROT-SJOGREN PRIMAIRE

Translated title of the contribution: Predominance of IgG1 subclasse among anti-Ro/SSA and anti-La/SSB antibodies during primary Gougerot-Sjogren syndrome

R. Maran, Y. L. Pennec, M. Dueymes, Y. Shoenfeld, P. Youinou

Research output: Contribution to journalArticlepeer-review

Abstract

Isotype-specific enzyme-linked immunosorbent assays have been developed to assess anti-Ro/SSA and anti-La/SSB IgG subclasses in 31 patients with primary Sjogren's syndrome. The anti-Ro/SSA antibody production was largely restricted IgG1, whilst the anti-La/SSB subclass distribution varied from one patient to another. IgG2 and IgG3 anti-La/SSB were more frequent in those patients with extraglandular complications.

Translated title of the contributionPredominance of IgG1 subclasse among anti-Ro/SSA and anti-La/SSB antibodies during primary Gougerot-Sjogren syndrome
Original languageFrench
Pages (from-to)446
Number of pages1
JournalRevue de Medecine Interne
Volume14
Issue number6
StatePublished - 1993
Externally publishedYes

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