Isotype-specific enzyme-linked immunosorbent assays have been developed to assess anti-Ro/SSA and anti-La/SSB IgG subclasses in 31 patients with primary Sjogren's syndrome. The anti-Ro/SSA antibody production was largely restricted IgG1, whilst the anti-La/SSB subclass distribution varied from one patient to another. IgG2 and IgG3 anti-La/SSB were more frequent in those patients with extraglandular complications.
|Translated title of the contribution||Predominance of IgG1 subclasse among anti-Ro/SSA and anti-La/SSB antibodies during primary Gougerot-Sjogren syndrome|
|Number of pages||1|
|Journal||Revue de Medecine Interne|
|State||Published - 1993|