Predictive value of placebo methylphenidate

Emanuel Tirosh, Ronit Elhasid, Sarah Cohen Bar Kamah, Ayala Cohen

Research output: Contribution to journalArticlepeer-review


The effects of methylphenidate in 20 children with attention-deficit disorder between the ages of 7 and 12 years were assessed in a double-blind, placebo/drug counterbalanced study. Measures of outcome included the Teacher Rating Scale and Abbreviated Parent Rating Scale: digits, words, and visual sequencing; motor control; and a maze test. The Teacher Rating Scale placebo-drug difference correlated more significantly with the outcome measures than the baseline-drug difference. The study underlines the validity of a multimeasure placebo/drug trial in evaluating the efficacy of methylphenidate in children with attention-deficit disorder.

Original languageEnglish
Pages (from-to)131-133
Number of pages3
JournalPediatric Neurology
Issue number2
StatePublished - 1993
Externally publishedYes


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