TY - JOUR
T1 - Predicting molecular interactions in silico
T2 - II. Protein-protein and protein-drug docking
AU - Schneidman-Duhovny, Dina
AU - Nussinov, Ruth
AU - Wolfson, Haim J.
PY - 2006/1
Y1 - 2006/1
N2 - This article reviews the docking field starting from basic docking algorithms and describing the latest advances. We present the algorithmic framework and classify the state of-the-art methods. We point out the bottlenecks of the methods, like flexibility, absence of absolute scoring functions and explain what types of information can potentially be added to improve the results. All rights reserved -
AB - This article reviews the docking field starting from basic docking algorithms and describing the latest advances. We present the algorithmic framework and classify the state of-the-art methods. We point out the bottlenecks of the methods, like flexibility, absence of absolute scoring functions and explain what types of information can potentially be added to improve the results. All rights reserved -
KW - Active site detection
KW - Biomolecular recognition
KW - Computer-aided design
KW - Flexibility
KW - Protein-ligand docking
KW - Protein-protein docking
UR - http://www.scopus.com/inward/record.url?scp=40249093606&partnerID=8YFLogxK
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AN - SCOPUS:40249093606
SN - 1567-2042
VL - 3
SP - 585
EP - 613
JO - Frontiers in Medicinal Chemistry
JF - Frontiers in Medicinal Chemistry
IS - 1
ER -