Predicted effects on herbicide binding of amino acid substitutions in the D1 protein of photosystem II

Amnon Horovitz, Nir Ohad, Joseph Hirschberg

Research output: Contribution to journalArticlepeer-review

Abstract

The effects of an amino acid substitution in the D1 protein of photosystem II on its binding to different herbicides are here successfully predicted. This is done by assuming additivity in the contributions to the binding energy of the amino acids at positions 255 and 264 of this protein which are part of the herbicide binding niche. Additivity in D1 protein-herbicide interactions is demonstrated, thus indicating an apparent lack of interactions between the amino acids at these two positions.

Original languageEnglish
Pages (from-to)161-164
Number of pages4
JournalFEBS Letters
Volume243
Issue number2
DOIs
StatePublished - 30 Jan 1989
Externally publishedYes

Keywords

  • Herbicide resistance
  • Photosystem II
  • Protein engineering
  • Protein, D1
  • Site-specific mutagenesis

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