Precision health: A pragmatic approach to understanding and addressing key factors in autoimmune diseases

Karsten Conrad, Yehuda Shoenfeld, Marvin J. Fritzler*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

The past decade has witnessed a significant paradigm shift in the clinical approach to autoimmune diseases, lead primarily by initiatives in precision medicine, precision health and precision public health initiatives. An understanding and pragmatic implementation of these approaches require an understanding of the drivers, gaps and limitations of precision medicine. Gaining the trust of the public and patients is paramount but understanding that technologies such as artificial intelligences and machine learning still require context that can only be provided by human input or what is called augmented machine learning. The role of genomics, the microbiome and proteomics, such as autoantibody testing, requires continuing refinement through research and pragmatic approaches to their use in applied precision medicine.

Original languageEnglish
Article number102508
JournalAutoimmunity Reviews
Volume19
Issue number5
DOIs
StatePublished - May 2020

Keywords

  • Autoantibodies
  • Autoimmune diseases
  • Autoinflammatory diseases
  • Biomarker
  • Precision health
  • Precision medicine

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