Practical issues drawn from the implementation of the integrated test for Down syndrome screening into routine clinical practice

B. Weisz; P. Pandya; L. Chitty; P. Jones; W. Huttly; C. Rodeck

doi:10.1111/j.1471-0528.2007.01238.x

Practical issues drawn from the implementation of the integrated test for Down syndrome screening into routine clinical practice

B. Weisz, P. Pandya^*, L. Chitty, P. Jones, W. Huttly, C. Rodeck

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

We have evaluated a cohort of women booked for antenatal care at University College London Hospitals. The uptake of screening was 64.4% and was significantly higher (73 versus 46%) in women who booked before 14 weeks. Of the women who booked before 14 weeks, 96.8% opted for the integrated test (IT). Overall, 5.3% failed to attend for the second blood test. The false-positive rate in the women who had the IT was 2.9%. All 11 cases of Down syndrome were detected prenatally. Our study is the first to evaluate implementation of the IT into routine clinical practice.

Original language	English
Pages (from-to)	493-497
Number of pages	5
Journal	BJOG: An International Journal of Obstetrics and Gynaecology
Volume	114
Issue number	4
DOIs	https://doi.org/10.1111/j.1471-0528.2007.01238.x
State	Published - Apr 2007
Externally published	Yes

Keywords

Down syndrome
Integrated test
Nuchal translucency
Screening

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10.1111/j.1471-0528.2007.01238.x

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abstract = "We have evaluated a cohort of women booked for antenatal care at University College London Hospitals. The uptake of screening was 64.4% and was significantly higher (73 versus 46%) in women who booked before 14 weeks. Of the women who booked before 14 weeks, 96.8% opted for the integrated test (IT). Overall, 5.3% failed to attend for the second blood test. The false-positive rate in the women who had the IT was 2.9%. All 11 cases of Down syndrome were detected prenatally. Our study is the first to evaluate implementation of the IT into routine clinical practice.",

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AU - Rodeck, C.

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Practical issues drawn from the implementation of the integrated test for Down syndrome screening into routine clinical practice

Abstract

Keywords

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