Prédominance de la sous-classe IgG1 parmi les anticorps anti-Ro/SSA, mais pas parmi les anticorps anti-La/SSB, au cours du syndrome de Gougerot-Sjögren primaire

R. Maran*, Y. L. Pennec, M. Dueymes, Y. Shoenfeld, P. Youinou

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Isotype-specific enzyme-linked immunosorbent assays have been developed to assess anti-Ro/SSA and anti-La/SSB IgG subclasses in 31 patients with primary Sjögren's syndrome. The anti-Ro/SSA antibody production was largely restricted to IgG1, whilst the anti-La/SSB subclass distribution varied from one patient to another. IgG2 and IgG3 anti-La/SSB were more frequent in those patients with extraglandular complications.

Original languageFrench
Pages (from-to)446
Number of pages1
JournalRevue de Medecine Interne
Issue number6
StatePublished - Jun 1993
Externally publishedYes

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