Postsplenectomy splenic activity

R. Orda, J. Barak, J. Baron, Z. Spirer, T. Wiznitzer

Research output: Contribution to journalArticlepeer-review


Evidence of recurring activity of splenic tissue was investigated in patients who had undergone splenectomies. Methods included technetium 99m sulfur colloid scan, serum tuftsin assay, serum immunoglobulin concentration, blood cell counts, and search for Howell-Jolly bodies. Positive scans were observed together with normal levels of tuftsin in 54% of the patients. In 46% of the patients, no splenic activity was detected by scanning and low levels of tuftsin were noticed. The difference in tuftsin levels between the two groups was statistically significant. Howell-Jolly bodies and decreased serum levels of IgM featured all patients. The possible application of combined splenic scan and tuftsin assessment for screening recurring splenic activity in the postsplenectomy population at great risk is suggested.

Original languageEnglish
Pages (from-to)771-774
Number of pages4
JournalUnknown Journal
Issue number6
StatePublished - 1981


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