Postpartum angina-like symptom complex associated with Syntometrine®

D. Soriano, M. Dulitzki, I. Tur-Kaspa, G. Barkai, S. Mashiach, D. S. Seidman*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


An angina-like symptom complex, characterized by chest pain, shortness of breath, nausea, vomiting and electrocardiogram changes, is a rare event in the immediate postpartum period. We prospectively followed all consecutive births at a single obstetric ward over a 4-month period. All 2640 women routinely received intramuscular Syntometrine® (ergometrine maleate 0.5 mg and oxytocin 5 IU) at the end of the third stage of labor. Twelve (0.45%) of the women reported chest pain and at least two complaints from the above symptom complex within 60 min of Syntometrine administration. The symptoms resolved spontaneously and no long-term complications were observed. We conclude that postpartum administration of Syntometrine may be associated with a self-limited angina-like symptom complex.

Original languageEnglish
Pages (from-to)60-62
Number of pages3
JournalPrenatal and Neonatal Medicine
Issue number1
StatePublished - 1997


  • Angina-like symptoms
  • Postpartum
  • Syntometrine


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