Postoperative rhabdomyolysis in patients with end-stage renal failure

Yaacov Ori, Asher Korzets, Carlos Gruzman, Avry Chagnac, Dina Zevin, Talia Weinstein, Michal Herman, Uzi Gafter

Research output: Contribution to journalArticlepeer-review

Abstract

Four patients with end-stage renal failure on intermittent hemodialysis in whom rhabdomyolysis developed after major surgery are described. This possibly underdiagnosed complication was manifested by extreme hyperphosphatemia, hypocalcemia, and elevated creatine phosphokinase levels. Serum myoglobin levels further supported the diagnosis. The metabolic abnormalities reached a peak on the fourth postoperative day. The possible precipitating factors included opiates used for anesthesia and postoperative pain control, anesthetic agents, and surgical position. The preferred treatment option is increasing dialysis to control hyperphosphatemia and hypocalcemia.

Original languageEnglish
Pages (from-to)539-544
Number of pages6
JournalAmerican Journal of Kidney Diseases
Volume31
Issue number3
DOIs
StatePublished - Mar 1998
Externally publishedYes

Keywords

  • End-stage renal failure
  • Rhabdomyolysis
  • Surgery

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