Post-traumatic stress disorder: Facts and fiction

Joseph Zohar, Alzbeta Juven-Wetzler, Vicki Myers, Leah Fostick

Research output: Contribution to journalReview articlepeer-review


PURPOSE OF REVIEW: This review provides an update on contemporary perspectives on post-traumatic stress disorder and challenges myths about the disorder and its treatment. Post-traumatic stress disorder has recently attracted public attention because of the impact of international terrorism, although the vast majority of post-traumatic stress disorder cases actually relate to civilian events such as car accidents, rape and violent robbery. This disorder requires deeper understanding and consensus among professionals. RECENT FINDINGS: Advances have been made in elucidating the neurobiology of this disorder, partly by using an animal model of post-traumatic stress disorder. Recent studies have focused on memory processes and the therapeutic role played by plasticity of the hypothalamic-pituitary-adrenal axis, and how this fits (or does not fit) in with the current therapeutic interventions. Guidelines have been established by various bodies in an attempt to streamline treatment options. SUMMARY: Understanding of post-traumatic stress disorder is incomplete. Future research should attempt to determine what treatments given during the 'window of opportunity' - the time from exposure until post-traumatic stress disorder develops - are effective. Care should be taken not to interfere with spontaneous recovery.

Original languageEnglish
Pages (from-to)74-77
Number of pages4
JournalCurrent Opinion in Psychiatry
Issue number1
StatePublished - Jan 2008
Externally publishedYes


  • Animal model
  • Benzodiazepines
  • Hypothalamic-pituitary-adrenal axis
  • Post-traumatic stress disorder


Dive into the research topics of 'Post-traumatic stress disorder: Facts and fiction'. Together they form a unique fingerprint.

Cite this