TY - JOUR
T1 - Post-streptococcal reactive arthritis in children
T2 - A distinct entity from acute rheumatic fever
AU - Uziel, Yosef
AU - Perl, Liat
AU - Barash, Judith
AU - Hashkes, Philip J.
PY - 2011/10/20
Y1 - 2011/10/20
N2 - There is a debate whether post-streptococcal reactive arthritis (PSRA) is a separate entity or a condition on the spectrum of acute rheumatic fever (ARF). We believe that PSRA is a distinct entity and in this paper we review the substantial differences between PSRA and ARF. We show how the demographic, clinical, genetic and treatment characteristics of PSRA differ from ARF. We review diagnostic criteria and regression formulas that attempt to classify patients with PSRA as opposed to ARF. The important implication of these findings may relate to the issue of prophylactic antibiotics after PSRA. However, future trials will be necessary to conclusively answer that question.
AB - There is a debate whether post-streptococcal reactive arthritis (PSRA) is a separate entity or a condition on the spectrum of acute rheumatic fever (ARF). We believe that PSRA is a distinct entity and in this paper we review the substantial differences between PSRA and ARF. We show how the demographic, clinical, genetic and treatment characteristics of PSRA differ from ARF. We review diagnostic criteria and regression formulas that attempt to classify patients with PSRA as opposed to ARF. The important implication of these findings may relate to the issue of prophylactic antibiotics after PSRA. However, future trials will be necessary to conclusively answer that question.
UR - http://www.scopus.com/inward/record.url?scp=80054683153&partnerID=8YFLogxK
U2 - 10.1186/1546-0096-9-32
DO - 10.1186/1546-0096-9-32
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AN - SCOPUS:80054683153
SN - 1546-0096
VL - 9
JO - Pediatric Rheumatology
JF - Pediatric Rheumatology
M1 - 32
ER -