Post infectious CNS disorders: Towards a unified approach

Marc Gotkine, Peter G.E. Kennedy, Israel Steiner

Research output: Contribution to journalReview articlepeer-review

Abstract

The spectrum of post infectious (PI) central nervous system (CNS) conditions includes a range of grey and white-matter disorders which can occur after viral or bacterial infections or in response to vaccinations. The clinical, radiological and immunological phenomenology raises a number of issues regarding the nature of immune-mediated CNS abnormalities, their etiology, pathogenesis and therapy. Here we focus on crucial issues pertaining to pathogenesis and aim to identify where current knowledge is insufficient in order to suggest future avenues of clinical and experimental research that may help to devise optimal therapy for these conditions.

Original languageEnglish
Pages (from-to)1963-1969
Number of pages7
JournalJournal of Neurology
Volume257
Issue number12
DOIs
StatePublished - Dec 2010

Keywords

  • Central nervous system
  • Demyelination
  • Infections
  • Post infectious

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