Positive serology for chlamydia: Is it always for chlamydia trachomatis?

Zvi Katz; Rony Levy; Samuel Lurie

doi:10.1159/000292424

Positive serology for chlamydia: Is it always for chlamydia trachomatis?

Zvi Katz, Rony Levy, Samuel Lurie^*

^*Corresponding author for this work

Kaplan Medical Center Israel

Research output: Contribution to journal › Article › peer-review

Abstract

n this study we tried to determine the factual prevalence of Chlamydia trachomatis seropositive women. Sera of 174 sexually active women of reproductive age who attended the emergency room in our gynecology department were tested by both a species-specific solid-phase enzyme immunoassay (SPEIA, ImmunoComb, Orgenics, Israel) and by an immunoperoxidase assay (IPA). One-hundred and twenty-two of 174 women (70.1%) tested were found positive for C trachomatis by the IPA test. The SPEIA test identified 41 (33.6%) of those as positive for C. trachomatis and 81 (66.4%) positive for C. pneumoniae. We conclude that the currently used IPA method for chlamydia diagnosis overestimates C. trachomatis infection and its specificity for the diagnosis of C. trachomatis is limited. By using the SPEIA test, it is possible to distinguish between C. trachomatis and C. pneumoniae seropositivity.

Original language	English
Pages (from-to)	271-273
Number of pages	3
Journal	Gynecologic and Obstetric Investigation
Volume	39
Issue number	4
DOIs	https://doi.org/10.1159/000292424
State	Published - 1995
Externally published	Yes

Keywords

Antibody
Chlamydia

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1159/000292424

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@article{f785375547c149a18482920376450236,

title = "Positive serology for chlamydia: Is it always for chlamydia trachomatis?",

abstract = "n this study we tried to determine the factual prevalence of Chlamydia trachomatis seropositive women. Sera of 174 sexually active women of reproductive age who attended the emergency room in our gynecology department were tested by both a species-specific solid-phase enzyme immunoassay (SPEIA, ImmunoComb, Orgenics, Israel) and by an immunoperoxidase assay (IPA). One-hundred and twenty-two of 174 women (70.1%) tested were found positive for C trachomatis by the IPA test. The SPEIA test identified 41 (33.6%) of those as positive for C. trachomatis and 81 (66.4%) positive for C. pneumoniae. We conclude that the currently used IPA method for chlamydia diagnosis overestimates C. trachomatis infection and its specificity for the diagnosis of C. trachomatis is limited. By using the SPEIA test, it is possible to distinguish between C. trachomatis and C. pneumoniae seropositivity.",

keywords = "Antibody, Chlamydia",

author = "Zvi Katz and Rony Levy and Samuel Lurie",

year = "1995",

doi = "10.1159/000292424",

language = "אנגלית",

volume = "39",

pages = "271--273",

journal = "Gynecologic and Obstetric Investigation",

issn = "0378-7346",

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TY - JOUR

T1 - Positive serology for chlamydia

T2 - Is it always for chlamydia trachomatis?

AU - Katz, Zvi

AU - Levy, Rony

AU - Lurie, Samuel

PY - 1995

Y1 - 1995

N2 - n this study we tried to determine the factual prevalence of Chlamydia trachomatis seropositive women. Sera of 174 sexually active women of reproductive age who attended the emergency room in our gynecology department were tested by both a species-specific solid-phase enzyme immunoassay (SPEIA, ImmunoComb, Orgenics, Israel) and by an immunoperoxidase assay (IPA). One-hundred and twenty-two of 174 women (70.1%) tested were found positive for C trachomatis by the IPA test. The SPEIA test identified 41 (33.6%) of those as positive for C. trachomatis and 81 (66.4%) positive for C. pneumoniae. We conclude that the currently used IPA method for chlamydia diagnosis overestimates C. trachomatis infection and its specificity for the diagnosis of C. trachomatis is limited. By using the SPEIA test, it is possible to distinguish between C. trachomatis and C. pneumoniae seropositivity.

AB - n this study we tried to determine the factual prevalence of Chlamydia trachomatis seropositive women. Sera of 174 sexually active women of reproductive age who attended the emergency room in our gynecology department were tested by both a species-specific solid-phase enzyme immunoassay (SPEIA, ImmunoComb, Orgenics, Israel) and by an immunoperoxidase assay (IPA). One-hundred and twenty-two of 174 women (70.1%) tested were found positive for C trachomatis by the IPA test. The SPEIA test identified 41 (33.6%) of those as positive for C. trachomatis and 81 (66.4%) positive for C. pneumoniae. We conclude that the currently used IPA method for chlamydia diagnosis overestimates C. trachomatis infection and its specificity for the diagnosis of C. trachomatis is limited. By using the SPEIA test, it is possible to distinguish between C. trachomatis and C. pneumoniae seropositivity.

KW - Antibody

KW - Chlamydia

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SN - 0378-7346

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JO - Gynecologic and Obstetric Investigation

JF - Gynecologic and Obstetric Investigation

IS - 4

ER -

Positive serology for chlamydia: Is it always for chlamydia trachomatis?

Abstract

Keywords

UN SDGs

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