@article{c60155b856a245c586725481d981b82e,
title = "Poly(dG)-poly(dC) DNA appears shorter than poly(dA)-poly(dT) and possibly adopts an A-related conformation on a mica surface under ambient conditions",
abstract = "Three types of DNA: ∼2700 bp polydeoxyguanylic olydeoxycytidylic acid [poly(dG)-poly(dC)], ∼2700 bp polydeoxyadenylic polydeoxythymidylic acid [poly(dA)-poly(dT)] and 2686 bp linear plasmid pUC19 were deposited on a mica surface and imaged by atomic force microscopy. Contour length measurements show that the average length of poly(dG)-poly(dC) is ∼30% shorter than that of poly(dA)-poly(dT) and the plasmid. This led us to suggest that individual poly(dG)-poly(dC) molecules are immobilized on mica under ambient conditions in a form which is likely related to the A-form of DNA in contrast to poly(dA)-poly(dT) and random sequence DNA which are immobilized in a form that is related to the DNA B-form.",
keywords = "A-form, Atomic force microscopy (AFM), DNA imaging, Poly(dA)-poly(dT), Poly(dG)-poly(dC)",
author = "Natalia Borovok and Tatiana Molotsky and Jamal Ghabboun and Hezy Cohen and Danny Porath and Alexander Kotlyar",
note = "Funding Information: We thank Igor Brodsky for assistance and fruitful discussions. The work was supported by the EC through Contracts IST-2001-38951 (“DNA-Based Nanowires”) and FP6-029192 (“DNA-Based Nanodevices”).",
year = "2007",
month = dec,
day = "22",
doi = "10.1016/j.febslet.2007.11.058",
language = "אנגלית",
volume = "581",
pages = "5843--5846",
journal = "FEBS Letters",
issn = "0014-5793",
publisher = "John Wiley and Sons Inc.",
number = "30",
}