Platelet X-ray microanalysis in patients with chronic renal failure

Meir Djaldetti*, Pnina Fishman, Draga Creter, Izhar Zahavi, Dina Zevin, Joseph Levi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The platelet element content was determined by semiquantitative X-ray microanalysis in 6 patients with chronic renal failure. The patients showed a different degree of thrombocytopathy expressed by impaired adhesiveness, epinephrine-induced aggregation and platelet factor 3 availability. The microanalysis indicated significantly increased quantities of phosphorus and copper in patients' platelets. Sodium and zinc showed a decrease in about half of the patients, whereas iron was significantly increased in at least 50% of the patients. Magnesium and potassium did not show any difference from the control. The results of sulfur, chlorine and calcium did not reveal a consistent pattern.

Original languageEnglish
Pages (from-to)213-217
Number of pages5
JournalActa Haematologica
Volume74
Issue number4
DOIs
StatePublished - 1985

Keywords

  • Chronic renal failure
  • Copper
  • Phosphorus
  • Platelet function
  • Platelet microanalysis
  • Sodium
  • Thrombocytopathy
  • Zinc

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