Platelet vesicular monoamine transporter density in untreated patients diagnosed with social phobia

Neil Laufer; Michal Zucker; Haggai Hermesh; Sofi Marom; Royi Gilad; Vered Nir; Abraham Weizman; Moshe Rehavi

doi:10.1016/j.psychres.2005.05.004

Platelet vesicular monoamine transporter density in untreated patients diagnosed with social phobia

Neil Laufer, Michal Zucker, Haggai Hermesh, Sofi Marom, Royi Gilad, Vered Nir, Abraham Weizman, Moshe Rehavi

Physiology Pharmacology

Research output: Contribution to journal › Article › peer-review

Abstract

The vesicular monoamine transporter (VMAT2) is important in the storage and release of monoamines. Platelet VMAT2 was characterized using high-affinity [³H]dihydrotetrabenazine ([³H]TBZOH) binding in untreated social phobia (SP) patients (n = 20) compared with sex- and age-matched healthy controls (n = 15). No significant differences in VMAT2 density (B_max) and affinity constants (K_d) were observed.

Original language	English
Pages (from-to)	247-250
Number of pages	4
Journal	Psychiatry Research
Volume	136
Issue number	2-3
DOIs	https://doi.org/10.1016/j.psychres.2005.05.004
State	Published - 15 Sep 2005

Keywords

Platelet
Social phobia
Vesicular monoamine transporter
[ H]dihydrotetrabenazine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.psychres.2005.05.004

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title = "Platelet vesicular monoamine transporter density in untreated patients diagnosed with social phobia",

abstract = "The vesicular monoamine transporter (VMAT2) is important in the storage and release of monoamines. Platelet VMAT2 was characterized using high-affinity [3H]dihydrotetrabenazine ([3H]TBZOH) binding in untreated social phobia (SP) patients (n = 20) compared with sex- and age-matched healthy controls (n = 15). No significant differences in VMAT2 density (Bmax) and affinity constants (Kd) were observed.",

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AU - Laufer, Neil

AU - Zucker, Michal

AU - Hermesh, Haggai

AU - Marom, Sofi

AU - Gilad, Royi

AU - Nir, Vered

AU - Weizman, Abraham

AU - Rehavi, Moshe

PY - 2005/9/15

Y1 - 2005/9/15

N2 - The vesicular monoamine transporter (VMAT2) is important in the storage and release of monoamines. Platelet VMAT2 was characterized using high-affinity [3H]dihydrotetrabenazine ([3H]TBZOH) binding in untreated social phobia (SP) patients (n = 20) compared with sex- and age-matched healthy controls (n = 15). No significant differences in VMAT2 density (Bmax) and affinity constants (Kd) were observed.

AB - The vesicular monoamine transporter (VMAT2) is important in the storage and release of monoamines. Platelet VMAT2 was characterized using high-affinity [3H]dihydrotetrabenazine ([3H]TBZOH) binding in untreated social phobia (SP) patients (n = 20) compared with sex- and age-matched healthy controls (n = 15). No significant differences in VMAT2 density (Bmax) and affinity constants (Kd) were observed.

KW - Platelet

KW - Social phobia

KW - Vesicular monoamine transporter

KW - [ H]dihydrotetrabenazine

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VL - 136

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EP - 250

JO - Psychiatry Research

JF - Psychiatry Research

SN - 0165-1781

IS - 2-3

ER -

Platelet vesicular monoamine transporter density in untreated patients diagnosed with social phobia

Abstract

Keywords

UN SDGs

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