Platelet vesicular monoamine transporter density in untreated patients diagnosed with social phobia

Neil Laufer, Michal Zucker, Haggai Hermesh, Sofi Marom, Royi Gilad, Vered Nir, Abraham Weizman, Moshe Rehavi

Research output: Contribution to journalArticlepeer-review

Abstract

The vesicular monoamine transporter (VMAT2) is important in the storage and release of monoamines. Platelet VMAT2 was characterized using high-affinity [3H]dihydrotetrabenazine ([3H]TBZOH) binding in untreated social phobia (SP) patients (n = 20) compared with sex- and age-matched healthy controls (n = 15). No significant differences in VMAT2 density (Bmax) and affinity constants (Kd) were observed.

Original languageEnglish
Pages (from-to)247-250
Number of pages4
JournalPsychiatry Research
Volume136
Issue number2-3
DOIs
StatePublished - 15 Sep 2005

Keywords

  • Platelet
  • Social phobia
  • Vesicular monoamine transporter
  • [ H]dihydrotetrabenazine

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