Platelet vesicular monoamine transporter density in untreated patients diagnosed with social phobia

Neil Laufer; Michal Zucker; Haggai Hermesh; Sofi Marom; Royi Gilad; Vered Nir; Abraham Weizman; Moshe Rehavi

doi:10.1016/j.psychres.2005.05.004

Platelet vesicular monoamine transporter density in untreated patients diagnosed with social phobia

Neil Laufer, Michal Zucker, Haggai Hermesh, Sofi Marom, Royi Gilad, Vered Nir, Abraham Weizman, Moshe Rehavi^*

^*Corresponding author for this work

Tel Aviv University

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

The vesicular monoamine transporter (VMAT2) is important in the storage and release of monoamines. Platelet VMAT2 was characterized using high-affinity [³H]dihydrotetrabenazine ([³H]TBZOH) binding in untreated social phobia (SP) patients (n = 20) compared with sex- and age-matched healthy controls (n = 15). No significant differences in VMAT2 density (B_max) and affinity constants (K_d) were observed.

Original language	English
Pages (from-to)	247-250
Number of pages	4
Journal	Psychiatry Research
Volume	136
Issue number	2-3
DOIs	https://doi.org/10.1016/j.psychres.2005.05.004
State	Published - 15 Sep 2005

Keywords

Platelet
Social phobia
Vesicular monoamine transporter
[ H]dihydrotetrabenazine

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10.1016/j.psychres.2005.05.004

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title = "Platelet vesicular monoamine transporter density in untreated patients diagnosed with social phobia",

abstract = "The vesicular monoamine transporter (VMAT2) is important in the storage and release of monoamines. Platelet VMAT2 was characterized using high-affinity [3H]dihydrotetrabenazine ([3H]TBZOH) binding in untreated social phobia (SP) patients (n = 20) compared with sex- and age-matched healthy controls (n = 15). No significant differences in VMAT2 density (Bmax) and affinity constants (Kd) were observed.",

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AU - Laufer, Neil

AU - Zucker, Michal

AU - Hermesh, Haggai

AU - Marom, Sofi

AU - Gilad, Royi

AU - Nir, Vered

AU - Weizman, Abraham

AU - Rehavi, Moshe

PY - 2005/9/15

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AB - The vesicular monoamine transporter (VMAT2) is important in the storage and release of monoamines. Platelet VMAT2 was characterized using high-affinity [3H]dihydrotetrabenazine ([3H]TBZOH) binding in untreated social phobia (SP) patients (n = 20) compared with sex- and age-matched healthy controls (n = 15). No significant differences in VMAT2 density (Bmax) and affinity constants (Kd) were observed.

KW - Platelet

KW - Social phobia

KW - Vesicular monoamine transporter

KW - [ H]dihydrotetrabenazine

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ER -

Platelet vesicular monoamine transporter density in untreated patients diagnosed with social phobia

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Keywords

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