Platelet monoamine oxidase activity in neuroleptic-naive schizophrenic patients: Lack of influence of chronic perphenazine treatment

B. Spivak, N. Kosower, Y. Zipser, N. Shreiber-Schul, A. Apter, S. Tyano, A. Weizman

Research output: Contribution to journalArticlepeer-review

Abstract

We investigated the possible relationship between schizophrenia, neuroleptic treatment, and platelet monoamine oxidase (MAO) activity. Platelet MAO activity was similar in neuroleptic-naive schizophrenic patients and healthy controls and was not affected by chronic (10-week) perphenazine treatment. A relationship between platelet MAO activity and central disturbances in schizophrenia remains uncertain.

Original languageEnglish
Pages (from-to)83-88
Number of pages6
JournalClinical Neuropharmacology
Volume17
Issue number1
DOIs
StatePublished - 1994
Externally publishedYes

Keywords

  • Monoamine oxidase
  • Perphenazine
  • Platelets
  • Schizophrenia

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