Platelet Hyperreactivity and Prognosis in Survivors of Myocardial Infarction

Jonathan M. Schapiro, Nadir Arber, Yechezkel Sidi, Mieke D. Trip, Volkert Manger Cats, Frans J.l. Van Capelle, Johan Vreeken

Research output: Contribution to journalLetterpeer-review


To the Editor: Trip and colleagues (May 31 issue)* are to be complimented on their important findings regarding the prognostic value of spontaneous platelet aggregation (SPA). We would like, however, to note a number of reservations. Although the study found significant results in a cohort of 149 patients, only 27 women were included in the study, of whom only 5 were in the SPA-positive group. In the entire female group there were only two deaths and four cardiac events. We do not believe that significant results can be obtained from such a small sample, and suggest that the findings be.

Original languageEnglish
Pages (from-to)1707
Number of pages1
JournalNew England Journal of Medicine
Issue number24
StatePublished - 13 Dec 1990
Externally publishedYes


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