Plasmid-mediated qnrB2 and carbapenemase gene blaKPC-2 carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates

Inna Chmelnitsky, Shiri Navon-Venezia, Jacob Strahilevitz, Yehuda Carmeli*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Fourteen out of 16 carbapenem-resistant quinolone-susceptible Enterobacter cloacae isolates were found to carry qnrB2 and blaKPC-2 genes encoded on the same plasmid. One isolate also carried the aac(6′)-Ib-cr gene. Coexistence of quinolone resistance determinants and blaKPC-2 on the same plasmid in quinolone-susceptible E. cloacae isolates may have important clinical implications.

Original languageEnglish
Pages (from-to)2962-2965
Number of pages4
JournalAntimicrobial Agents and Chemotherapy
Volume52
Issue number8
DOIs
StatePublished - Aug 2008
Externally publishedYes

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