TY - JOUR
T1 - Plasma norepinephrine levels in patients with sleep apnea syndrome
AU - Eisenberg, E.
AU - Zimlichman, R.
AU - Lavie, Peretz
PY - 1990/3/29
Y1 - 1990/3/29
N2 - To the Editor: Patients with sleep apnea syndrome often have an increased incidence of cardiac arrhythmias and hypertension.1 These cardiovascular complications may be produced by increased sympathetic activity in response to hypoxemia during apnea. Since plasma and urinary norepinephrine levels are considered to reflect sympathetic activity, recent studies have focused on urinary and plasma norepinephrine levels in sleep apnea syndrome.2,3 The purpose of this study was to investigate the relation between nocturnal plasma norepinephrine levels and the severity of sleep apnea syndrome, as reflected by the apnea index and decrease in blood oxygenation. We studied eight men with sleep apnea.
AB - To the Editor: Patients with sleep apnea syndrome often have an increased incidence of cardiac arrhythmias and hypertension.1 These cardiovascular complications may be produced by increased sympathetic activity in response to hypoxemia during apnea. Since plasma and urinary norepinephrine levels are considered to reflect sympathetic activity, recent studies have focused on urinary and plasma norepinephrine levels in sleep apnea syndrome.2,3 The purpose of this study was to investigate the relation between nocturnal plasma norepinephrine levels and the severity of sleep apnea syndrome, as reflected by the apnea index and decrease in blood oxygenation. We studied eight men with sleep apnea.
UR - http://www.scopus.com/inward/record.url?scp=0025305438&partnerID=8YFLogxK
U2 - 10.1056/NEJM199003293221314
DO - 10.1056/NEJM199003293221314
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C2 - 2314430
AN - SCOPUS:0025305438
SN - 0028-4793
VL - 322
SP - 932
EP - 933
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 13
ER -